When sending email through SendSuite® Xpress, Ascent, or SendSuite® Arrival, a Microsoft Office Outlook security message may be displayed with the message "A program is trying to access e-mail address information stored in Outlook. If this is unexpected, click Deny and verify your antivirus software is up-to-date."
Example:

To proceed and allow the email to be sent, select
Allow.
This message will continue to appear until your system is configured to bypass it. Contact software support to have your system configured to bypass this message.
UPDATED: August 07, 2017